What cities are the most conducive to scientific research?

A new study in Nature examines which cities are the best for scientific research. The article cites some different measures to get at things like output and quality. Here are some of the findings:

-The top cities for number of articles produced: “Tokyo, London, Beijing, the San Francisco Bay Area, Paris and New York.”

-The top cities based on quality of research (measured as average citations of articles): “Boston and Cambridge, Massachusetts, come out on top — attracting more than twice as many citations per paper as the global average. US cities dominate the quality table, with only Cambridge, UK, breaking into the top 10. Cities with the most improved relative quality in the past decade include Austin, Texas, and Singapore City — which has moved from 15% below average to 22% above it. Beijing, however, is below par in the quality stakes: its papers in the five-year period ending 2008 attracted 63% of the global average-citation rate.”

-According to a sociologist, the three factors that lead to more research: “freedom, funding, and lifestyle.”

Several of the experts also caution that cities shouldn’t just throw money at research in the expectation that this will lead to significant wealth generated for the city.

I wonder how much of a role historical factors play in this. Once a city acquires a reputation for prestigious universities and research (think: Boston), how quickly could it lose its status if drastic things started to take place (such as the bankruptcy of Harvard and MIT)? It seems like certain cities gain a reputation or character and that character becomes an inertia that continues to attract new research facilities and scientists.

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